What is the best schedule for microdosing?

The Fadiman protocol (one day on, two days off) and the Stamets stack (five days on, two days off) are the most widely used microdosing schedules.

Why are off-days important in microdosing protocols?

Off-days allow your serotonin receptors to reset, preventing tolerance buildup and maintaining the effectiveness of each dose.

Most practitioners recommend at least four to eight weeks of consistent microdosing before drawing conclusions about its effectiveness for you.

Keeping a daily journal noting mood, energy, focus, and sleep quality is the most effective way to track microdosing results.

Fadiman Protocol

1 day on, 2 days off

Stamets Stack

4 days on, 3 days off

Every Other Day

1 day on, 1 day off

Intuitive

As needed

Start Date

Duration (weeks)

Dosage (mg)