Psilocybin content varies by species and even by individual mushroom, but the most commonly cultivated species, Psilocybe cubensis, averages around 0.63% psilocybin by dry weight — roughly 6-7mg of psilocybin per gram of dried mushroom. A typical moderate recreational dose of 2-3.5g dried P. cubensis therefore delivers approximately 13-24mg of psilocybin, though potency can vary substantially between batches.
Important: Potency varies significantly between species, strains, and even individual specimens or flushes from the same batch. These figures are general educational estimates, not a personal dosing guide — actual content can only be confirmed through laboratory or reagent testing.
Average Potency of Psilocybe cubensis
Most dosage information available online, including on this site, is based on Psilocybe cubensis, the most widely cultivated psilocybin mushroom species. Cultivated P. cubensis averages approximately 0.63% psilocybin by dry weight, meaning one gram of dried mushroom contains roughly 6-7mg of psilocybin. However, potency in tested samples has ranged from about 0.2% up to over 1.5%, depending on the specific strain, growing conditions, and even which flush (harvest) the mushrooms came from.
Estimated Psilocybin Content by Common Dose Sizes
Using the ~0.63% average as a rough guide for dried P. cubensis:
- Microdose (0.05-0.3g): Approximately 0.3-2mg psilocybin
- Threshold/"museum" dose (0.5-1g): Approximately 3-6mg psilocybin
- Low dose (1-2g): Approximately 6-13mg psilocybin
- Moderate dose (2-3.5g): Approximately 13-24mg psilocybin
- High dose (3.5-5g): Approximately 24-32mg psilocybin
- "Heroic" dose (5g+): 32mg+ psilocybin
Why These Numbers Are Estimates, Not Guarantees
Because potency varies so much between strains, growing conditions, and even individual mushrooms within the same batch, gram weight alone is an imprecise proxy for actual psilocybin dose. The only way to know actual psilocybin content with confidence is through laboratory testing or reagent-based potency testing; without it, any gram-based dosing figure — including the ones above — should be treated as a rough estimate rather than a precise measurement, and it's why starting low and going slow matters even for someone with prior experience using a different batch or species.