Our Purpose
Psilobase is an independent educational resource focused on psilocybin mushrooms: their biology, pharmacology, history, safety profile, and evolving legal status. Our editorial priority is harm reduction — giving readers accurate, evidence-based information so they can make informed decisions, understand real risks, and know where to go for professional help when needed.
We do not provide medical, legal, or psychological advice. We do not sell products or endorse suppliers. We are not a crisis service. What we do is explain the science clearly, cite our sources, and keep the information as current and accurate as we can with a small volunteer team.
What Psilobase Covers
Mushroom Species
The species section covers the most commonly encountered psilocybin-containing mushrooms — taxonomy, habitat, distinguishing features, and critically, toxic lookalikes. Every species page includes an explicit warning about the risks of misidentification and directs readers to consult a professional mycologist for any identification question. We do not perform identifications.
Safety and Harm Reduction
Our safety section is the largest and most intensively reviewed part of the site. It covers:
- Contraindications — medical conditions, medications, and personal history factors that make psilocybin use significantly riskier
- Drug interactions — particularly dangerous combinations with lithium, MAOIs, and SSRIs
- Set and setting — the psychological and environmental factors that most strongly predict whether an experience is positive or difficult
- Emergency procedures — how to support someone in a difficult experience, how to distinguish psychological distress from medical emergency, and when to call emergency services
- Legal status — a regularly updated summary by jurisdiction, with clear caveats that it is not legal advice
Microdosing
The microdosing section explains the most commonly used protocols (Fadiman, Stamets stack, intuitive), tolerance dynamics, journaling methodology, and what current research does and does not support. We are careful to present emerging evidence fairly without overstating conclusions — the research base for microdosing is still developing, and we reflect that nuance.
Research
Research summaries cover the major clinical trial programmes — depression, addiction, end-of-life anxiety, PTSD — from institutions including Johns Hopkins, NYU, and Imperial College London. Each summary includes methodology, sample size, key findings, and limitations. We link to original publications wherever possible.
Cultivation and Preparation
Cultivation and preparation information is presented for educational purposes, reflecting that these activities are legal in some jurisdictions (spore possession, for example, is legal in many US states and UK). We include safety information about contamination risks, sterilisation, and the legal context in each section header.
Integration
Integration — the process of making meaning from and practically incorporating insights gained during a psilocybin experience — is covered with reference to established therapeutic frameworks (Internal Family Systems, ACT, somatic approaches) and community practices. Integration is often the most neglected aspect of harm reduction, and we treat it as essential.
How to Get the Most from Psilobase
Start with the section most relevant to your situation. If you are considering a first experience, the Safety section — particularly contraindications and set/setting — should be your first stop, before anything on dosing or species. If you are supporting someone else, the Safety and emergency procedures pages are most immediately useful.
Use the search function (or your browser’s find-on-page) to locate specific terms. The Glossary defines specialist terms used across the site. The FAQ addresses the most common questions in condensed form.
What We Cannot Help With
To keep our editorial team focused on producing and maintaining accurate content, there are clear limits to what Psilobase can provide:
- Medical advice: We cannot advise on whether psilocybin is safe for a specific individual, interpret symptoms, or recommend dosages tailored to a person’s situation. Consult a doctor, ideally one familiar with psychedelic medicine.
- Legal advice: Psilocybin’s legal status is complex and jurisdiction-specific. Our legal summaries are informational; for legal questions about your specific situation, consult a solicitor or attorney.
- Sourcing or procurement: We do not stock, sell, or endorse any supplier. We do not link to vendors.
- Species identification: Send photographs to a local mycological society or consult a professional mycologist. Misidentification of mushrooms can be fatal, and we are not qualified to assist.
- Real-time crisis support: If you or someone you know is in a mental health crisis or medical emergency, contact emergency services or a crisis line immediately — not a website.
Crisis Support Resources
If you need immediate help:
- Emergency services: 999 (UK) | 911 (US) | 112 (EU)
- Fireside Project (US, psychedelic crisis support): 623-473-7433 — free, confidential, daily 3 pm–3 am PT
- Samaritans (UK and Ireland): 116 123 — free, 24 hours
- Crisis Text Line (US/UK): Text HOME to 741741
- CALM (UK men’s crisis): 0800 58 58 58
Contacting the Team
For corrections, feedback, and collaboration enquiries, see the Contact page. We aim to respond to substantiated corrections within 5–10 business days. Please include the page URL, the passage in question, and a credible source for your correction. Press enquiries receive a faster response.
Safety Commitments
Psilobase commits to:
- Presenting dosage information conservatively, always noting that individual responses vary significantly
- Prominently flagging contraindications and interaction risks on relevant pages
- Reviewing legal content quarterly and following major policy changes as they occur
- Citing peer-reviewed sources for all clinical claims
- Not accepting advertising, sponsorship, or commercial relationships that could compromise editorial independence
- Collecting only anonymised, aggregate analytics data — no invasive tracking
Frequently Asked Questions
Is the information on this site medical advice?
No. All content is provided for educational purposes only. Nothing on Psilobase constitutes medical, legal, or professional advice. Always consult a qualified healthcare professional for personal medical questions.
Can you identify a mushroom for me?
No. Misidentification of mushrooms can be lethal. Please consult a professional mycologist or a local mycological society. Do not rely on website photos or descriptions for identification decisions.
Do you endorse any products or suppliers?
No. Psilobase does not accept advertising and does not link to or endorse any commercial supplier of substances, equipment, or services.
How often is legal information updated?
We aim to review legal content quarterly and update promptly when significant policy changes occur (for example, the Australian TGA rescheduling in 2023, or US state-level decriminalisation measures). Legal status information is a summary and not legal advice.
Why does Psilobase avoid definitive claims about outcomes?
Responses to psilocybin are highly variable — influenced by dose, individual neurochemistry, psychological history, set, and setting. Definitive statements about likely outcomes would be misleading. We present the range of evidence and encourage readers to discuss their specific situation with a qualified professional.
What if I find an error or outdated information?
Please contact us with the page URL, the passage in question, and a credible source for the correction. We review all substantiated corrections promptly and publish updates as quickly as the review process allows.
How does Psilobase handle my personal data?
We collect only anonymised, aggregate analytics. We do not use invasive tracking, and we do not sell or share personal data. Bookmarks and browsing history features are stored locally in your browser only — they are not transmitted to our servers. See our Privacy Policy for full details.